Merhaba Misafir

Application of heterocyclic compounds as catalysts in Suzuki-Miyaura cross-coupling reaction

PDF

Four different benzimidazolium salts (1-4) were prepared in three steps at 80 oC and their structures were elucidated using spectroscopic methods. The compounds (1-4) obtained were tested in in situ medium as catalyst in the carbon-carbon (C-C) bond formation reactions of two different boronic acid derivatives with various aryl halides in the presence of palladium acetate (PdOAc)2 and sodium tertiarybutoxide (NaOBut) as a base. With this reaction, four coupling products (5-8) were synthesized in different yields ranging from 11 to 93%. Compound 2 from the carbene precursors tested in the Suzuki-Miyaura cross-coupling reaction was found to be a more effective catalyst candidate than others.

Yayınlandığı Kaynak : Cumhuriyet Science Journal
  • Yıl : 2019
  • DOI : 10.17776/csj.613060
  • Cilt : 40
  • ISSN : 2587-2680
  • Sayı : 4
  • eISSN : 2587-246X
  • Sayfa Aralığı : 854-859
  • IO Kayıt No : 107160
  • Yayıncı : Cumhuriyet Üniversitesi